Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Not like opioids, which bind to µ-opioid receptors during the central anxious system, conolidine modulates alternate molecular targets. A Science Developments study identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://conolidine-for-ankle-pain69023.dbblog.net/12315136/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers