Summary: The recruitment of Polycomb repressive complex 2 (PRC2) to gene promoters is critical for its function in repressing gene expression in murine embryonic stem cells (mESCs). However. previous studies have demonstrated that although the expression of early lineage-specific genes is largely repressed. the genome-wide PRC2 occupancy is unexpectedly reduced in naive mESCs. https://www.itsmajorlook.com/