Below, we present that conolidine, a pure analgesic alkaloid Utilized in standard Chinese medicine, targets ACKR3, therefore supplying further proof of the correlation concerning ACKR3 and pain modulation and opening choice therapeutic avenues to the therapy of Long-term soreness. The initial asymmetric total synthesis of conolidine was formulated by https://christp947omv0.homewikia.com/user